The Covid vax contains a modified mRNA with a pseudo-uridine that gives this "messenger" a life extension of up to 60 days instead of the minutes or hours that natural messenger RNA lasts for.

Malone's contribution to mRNA synthesis was the brainwave that it could be used as a drug; he added a positively charged liposome to the mix that made for better cohesion (see Nature.com "The Tangled History of mRNA Vaccines, 9/14/21).